Kabul, Afghanistan (CNN)An attacker driving an ambulance packed with explosives detonated them in Kabul on Saturday, leaving 40 people dead and 140 others injured, Afghan officials said.
The blast occurred about 12:45 p.m. local time after the vehicle passed through a first security checkpoint, according to Interior Ministry spokesman Nasrat Rahimi.
Police identified the attacker at the second checkpoint but were unable to stop him before he detonated the explosives near the old Ministry of the Interior building, he said.
The injured have been taken to hospitals across the Afghan capital, said spokesman Wahid Majrooh of the Ministry of Public Health, who confirmed the casualties.
Taliban spokesman Zabiullah Mojahid claimed responsibility for the attack.
The blast comes a week after gunmen attacked the Intercontinental Hotel in Kabul, killing at least 22 people during a 12-hour standoff with security forces.
Of those killed, 14 were foreign nationals and eight were Afghans, according to the Ministry of Interior. Six gunmen were killed by Afghan security forces. The Taliban claimed responsibility for the assault.
On Wednesday, ISIS militants attacked the offices of British aid agency Save the Children in the eastern Afghan city of Jalalabad, killing at least four people and injuring dozens.